Quoting: Erathoniel
You could, but I'd prefer using cannon fodder and martial arts, personally, but not many people can rival a plasma cannon with their fist.
My first character in GearHead is a martial artist, with most of the points spent improving her kung fu.
That doesn't work too well though... it seems martial arts is a very specialized path to take in GH. You gotta devote yourself to it to succeed.
It's a habit from Fallout2... the first character I created is an unarmed specialist, with small guns as backup... that rocked and I finished the game on the first try. Later on I made many different characters, but all have points in unarmed.
Including one specializing in throwing... that one was fun. I gave him plenty of strength and perception to maximize the no. of grenades he could carry and the range he could throw to (with feats). He stuffed the car trunk with all the grenades he could find, and then grabbed as much as he could carry to face the Enclave. He won the final fight by himself.