Well, if we're on the topic of cheating on foot mecha takedowns, I'd say the times I (or anyone, if they do it right) trigger integer overflow from doing too much damage in a single attack and crashing the game probably kinda' wins the contest. Especially wit' jo' fists. Or feet. Whatever. Would like to be able to headbutt the things.
A spot weakness skill of 200+ will ruin anyone's day. (Well, to be fair, last time I did it, it doesn't take more than about 20. 200 is major, major overkill.)
So yeah. Martial arts. Nude. 1-shot TKO, utter destruction of all limbs, components, etc. I have screenies on my old laptop, kehe.
Now as for legit sf:0-sf:2 fights... well, pray they don't have blast weapons and load up a robot swarm with those AP/Brutal rocket launcher whatsits seems like it'd be easiest.
But really, a decent dodge'll probably carry the day for you if they don't have blast/line stuff. It's rather hard to hit tiny people, especially when there's 50 of them.