Scene: Hospital. Your grandfather, his mind marred by old age, asks you to find a "family heirloom" that doesn't exist. You speak with your parent/aunt/uncle and they reveal that it really does exist, but was hidden in the local -insert dungeon here-. The words of your grandfather carry great weight in the family, and if he thinks it's time for you to have it, then you must seek it out.
Scene: The bedroom of a respected local figure, or more precisely, his child. The door slams as they enter the house, ruining the "2 person party" you were holding. You can try to escape, hide, or take them on with a couple rounds of fisticuffs.
Scene: You burst out of the cryogenic pod about 10 years too late. Instead of being awoken to fight the -insert local bad guys-, you discover that they haven't been around for half a dozen years. You can decide to track them down and wipe them out, or get on with your life, but either way, they're going to crop up occasionally to make your life difficult.