I've noticed that in ASCII mode, at least, dialog options in conversations will sometimes go off the right edge of the textbox, preventing you from reading them. I forget which one in particular I noticed, but it was one in the very first conversation... they should probably wrap somehow or something.
On a related note, the ASCII-mode shop and inventory menus feel a little cramped. This is mainly, I think, because they're 'windowed' and devote several lines of space to showing the world around you... there doesn't really seem to be any need for this, as it's not showing you enough to be useful. There are two lines on the bottom in particular that would make things much easier if the item menu was expanded to use them. Things could also be expanded on the right a little bit, but that's not so important.
Oh, and when doing most targeting (either weapons or 't'alking) you can't use 'enter' to select your target, only 'space.' That gets sort of annoying.